The Inhibitory Effect of Genus Lactobacillus on Helicobacter Pylori Infection

The triple treatment of Helicobacter pylori infection with two antibiotics and PPI has been shown to be the best way to eradicate this bactirium. In the last years the antibiotic resistance is increasing. Metaanalyses on the effects of probiotics on the gastrointestinal diseases have shown positive effects on the prevention and treatment of these disease. Various studies support thе hypothesis that probiotics may inhibit H. pylori growth. The release of bacteriocins active against H. pylori has been studied chiefly in Lactobacillus, but probiotic bifidobacteria may also produce them. Probiotics reduce the side effects of H. pylori regimens and may slightly increase eradication success. The tradition of yogurt consumption has been related to longevity of some populations living on the Balkans. Probiotics have been claimed to exert anticarcinogenic activities, too. From the 4th Maastricht/Florence Consensus Conference in 2012 about the management of Helicobacter pylori infection: ”Certain probiotics and prebiotics show promising results as an adjuvant treatment in reducing side effects”.